Weight Loss Technique: Today everyone wants to keep the body healthy. Even if the weight increases, there is a risk of many diseases. To lose weight one should control the eating and drinking habits, change the lifestyle and do light exercises as much as possible.
But be careful if you are taking any medicine to lose weight. Wegovy and Ozempic, used for rapid weight loss, may carry a risk of serious side effects, a new American study has revealed. It can also cause abdominal paralysis. Abdominal paralysis often requires emptying of the stomach. Abdominal paralysis can cause sudden weight loss, malnutrition, and other complications, and treatment may even require surgery.
A major revelation in an American study
People who use Vegovi and Ozempic, known as GLP-1 agonist drugs, to lose weight, the study said. People who take these drugs may have a 30% increased risk of developing stomach paralysis. People who have taken this medicine Glucagon-like peptide-1 receptor agonists (GLP-1RAs), also known as GLP-1 agonists, are a class of drugs used to treat type-2 diabetes and obesity.
The report, presented at the medical conference Digestive Disease Week 2024 (Digestive Disease Week 2024) in Washington on Saturday, is based on an analysis of the records of more than three lakh people with diabetes and obesity, of whom 1.65 lakh were prescribed GLP-1 agonists. It also slows the process of emptying the stomach and is known to stimulate insulin production.
Be careful if you are taking medicines
University of Kansas Professor of Medicine Dr. Prateek Sharma said that there is a serious risk of stomach paralysis due to the side effect of this drug, but it is very important to warn people about it in view of overuse of GLP-1 drugs or weight loss drugs. Also 'these drugs are new, although they have been positively effective, we are still studying their long-term side effects. So I think people who are taking this medicine need to be very careful.
These drugs are available secretly in India
Wegovi and Ozempic are not legally available in India. However, according to reports, many people also buy these drugs from the gray market at a higher price. Recently, Novo Nordisk, a Danish company has launched 'Rybelsus' in tablet form in India, in which the main ingredient of Ozempic is Semaglutide. It is approved for diabetes management, but doctors say the drug is also being used 'off-label' for weight loss.
Vegovi and Ozempic were also initially approved for diabetes. But a report came out saying that this drug can help in 10-15% weight loss in a year. So the US FDA approved its limited use even in people with severe disease. Soon the drug group caused an uproar around the world, as some of the biggest celebrities, including Elon Musk and Oprah Winfrey, said, "We're using it."
Learn what Wegovi and Ozempic do
Dr. According to Randhir Sood, drugs like Vegovi and Ozempic start their action by slowing down the movement of the stomach. Thus reduces appetite. And when someone starts taking this drug, they experience nausea and vomiting, but in some cases these side effects were also less. He said. I have not yet come across any cases of stomach paralysis, but these are early days of its use in India.
Health related records of more than 12 crore patients were analyzed
In this US study, Sharma and colleagues used a large database to analyze the health records of more than 12 million patients, focusing on people with diabetes and obesity. They compared patients taking GLP-1 drugs with a control group. In which they obtained demographic and health factors. After one year, they found that 32% of GLP-1 users experienced gastrointestinal problems, such as nausea, GERD, and stomach cramps.
That is, while GLP-1 users underwent more GI-related procedures, they had fewer ER visits and hospital admissions. That is, while GLP-1 drugs increase GI side effects, they do not cause serious health problems that require emergency care or hospitalization.
Speaking about this, a professor from the University of Kansas said, 'We are not saying that it should not be used. But our research clearly shows that gastrointestinal side effects, such as stomach paralysis, which can impair a healthy life, require greater monitoring.'
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